• Classed as a proton pump inhibitor
  • Reduces symptoms of acid reflux
  • Helps to prevent cancer of the oesophagus
  • Genuine medication
  • All drugs sourced in the UK




Nexium is utilized in the treatment of certain stomach and oesophagus problems like ulcers, hyperacidity, indigestion, and more. As it works to help decrease the levels of acid in the stomach walls, it offers immediate relief to conditions such as persistent coughing, swallowing difficulties, and even heartburns.


What is Nexium?


Nexium or most commonly known as “The Purple Pill,” is the brand name for Esomeprazole manufactured by AztraZeneca. It is the most prescribed drug in the U.S. for the treatment of gastroesophageal reflux disease or acid reflux, peptic ulcer, indigestion, Zollinger-Ellison Syndrome, and other gastrointestinal diseases, because of its active ingredient called omeprazole

that is classified as proton pump inhibitor (PPI), which reduces the production of acid in our stomach. It was FDA approved and introduced to the public in 2015 with no prescription required. Since the generic name was patented in 1993, about eight pharmaceutical companies manufactured Nexium in several countries including the U.S., Europe, and Asia. 


Nexium is formulated and produced in capsule form which consists of tiny enteric-coated granules or pellets of the chemical formulation. When the capsule is swallowed, its outer shell will burst and the contents are absorbed through the stomach.  Although it can also administer through injection.


However, proper precaution is necessary when taking Nexium for long-term medication since evidence of long-term use of drugs shows danger and may cause serious health problems such as chronic kidney disease, stroke, and gastric cancer. 


How Does Nexium Work?


People suffering from persistent heartburn pain brought by acid reflux, the esomeprazole can work in wonder. The esomeprazole acting as a proton pump inhibitor, blocks the “acid pumps” in the wall of the stomach, which reduces the acid in the stomach and allowing the internal organs to heal. By calming the stomach from intense acid reflux, it prevents further damage to the esophagus. The capsule easily reacts by water absorption and any drug residue is rapidly cleared from the body, largely by excretion through urine.


However, Nexium may take 1 to 4 days to notice the full effect and does not immediately relieve heartburn right away. If you are self-medicating, over-the-counter esomeprazole products are used to treat frequent heartburn (occurring 2 or more days a week).


Who Can and Can’t Take Nexium?


Nexium is suitable for children and adults as approved by the Food and Drug Administration (FDA). Children age 1-11 years old can take 10mg or 20mg while children or pediatric patients age 12 -17 are recommended to take 20mg or 40mg.


The Nexium consists of esomeprazole magnesium, so, people should not take this medication if they have an allergic reaction to any of the drug components. Also, people who have an allergy to any other PPI should not take Nexium. These precautions and any questions about Nexium and other PPIs should be discussed with a medical professional.


What are the Benefits of Nexium?


Nexium relieves symptoms of heartburn. It also helps treat damage caused by acid reflux and prevents severe ulcers and cancer of the esophagus.


How Do I use Nexium?


The patient should follow the instruction written in the package before taking the Nexium. Always ask the doctor or pharmacist for any questions. Usually, the Nexium is taken orally, at least one hour before taking a meal. The dosage and length of treatment may vary depending on your medical condition and response to treatment. Avoid increasing your dose or take it more frequently than instructed. If you find difficulty swallowing the capsule, you may open it and blend the content into a tablespoon of fresh fruit juice. If you will do this option, make sure that you will consume the mixture immediately in one take. Prepare the fruit juice by the time you need to take the medicine and not prepare it ahead to avoid contaminating the drug. 


Take the Nexium regularly for more effective results. Choose the best time that is easy for you to remember and take it the same time each day. If you notice a quick response of the medicine and you are feeling better, just continue the medication for the prescribed length of treatment. However, do not take it more than 14 days unless prescribed by your doctor. 


If symptoms persist, consult your doctor for medical help.


Other Alternative of Nexium


AstraZeneca manufactures prescription versions of both Nexium and Prilosec. Prevacid and Protonix are two other related drugs.


  • Nexium, Nexium IV – require a prescription
  • Nexium 24HR – no prescription required


Other Over-the-Counter drugs that are also for the treatment of heartburn and excess stomach acid:

  • Zegerid (omeprazole and sodium bicarbonate) 
  • pantoprazole (pantoprazole) 
  • Zantac (ranitidine) 
  • Pepcid (famotidine) 
  • Tagamet (cimetidine) 
  • omeprazole (omeprazole)



Nexium Dosage


The Nexium (esomeprazole magnesium) capsules are available in low and high dosage. 


  • 10mg – lowest dosage for children age 1-11years old.


  • 20mg – over-the-counter acid-reducer; recommended for adults with Gastroesophageal reflux disease (GERD)
  • 40 mg – Nexium (esomeprazole magnesium) capsules


What are the Side Effects?


Like any other drug, Nexium has some side effects. Warnings and precautions in taking should be reviewed carefully before starting on the medication.


The most common side effects of Nexium may include:

  • Abdominal pain
  • Constipation
  • Diarrhea
  • Dry mouth
  • Flatulence
  • Headache
  • Nausea
  • Somnolence (drowsiness or sleepiness)


Serious side effects may include angioedema, Clostridium difficile infection, and pneumonia. Use in pregnancy appears to be safe, while safety during breastfeeding is not recommended. In a study conducted in 2017 where 125,000 PPI users were monitored within 5 years. Half of the patients who developed chronic kidney damage had never had kidney problems before taking PPIs. Long term used of Nexium can cause damage to the kidney. According to the FDA, it also increases the risk of the stomach lining and increases the risk of death.


The FDA warns that patients should never take Nexium 24HR for more than 14 days at a time. And they should never take more than three 14-day courses in a year. People should not take Nexium if they take certain other medicines. They should also avoid Nexium if they take certain dietary supplements.


Nexium interactions can affect how one or both substances perform. People should tell their doctor what drugs and supplements they are taking before using Nexium.


Nexium Can Interact with the Following Products

  • Any product that contains iron
  • Cellcept (mycophenolate mofetil)
  • Coumadin, Jantoven (warfarin)
  • Fortovase (saquinavir)
  • Lanoxin (digoxin)
  • Methotrexate
  • Nizoral (ketoconazole)
  • Plavix (clopidogrel)
  • Pletal (cilostazol)
  • Prograf (tacrolimus)
  • Reyataz (atazanavir)
  • Rimactane, Rifater, Rifamate (Rifampin)
  • St. John’s Wort (hypericum perforatum)
  • Tarceva (erlotinib)
  • Valium (diazepam)
  • Vfend (voriconazole)
  • Viracept (nelfinavir)


How Do I Buy Nexium Online?


Many virtual pharmacy stores allow you to purchase Nexium online. Find a legitimate online drugstore that you can trust. Make sure that before you obtain the drug, you are aware of any medical conditions you have or any medications you are taking since Nexium formulation may react to other types of products.

Please note: this page is only to be used as a reference of our price for this medication. If you are approved for General Health medication, you will be offered treatment for you and the prescriber to jointly consider. However, the final decision will always be the prescriber's.
  • All inclusive service

    No hidden fees

  • Free Tracked Delivery

    Delivered in plain packaging

  • Prescription included

    Via our online consultation